Adipolin/C1qdc2/CTRP12 Protein Functions as an Adipokine That Improves Glucose Metabolism

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Adipolin/C1qdc2/CTRP12 protein functions as an adipokine that improves glucose metabolism.

Obesity is a major risk factor for the development of insulin resistance and type 2 diabetes. Adipose tissue secretes various bioactive molecules, referred to as adipokines, whose dysregulation can mediate changes in glucose homeostasis and inflammatory responses. Here, we identify C1qdc2/CTRP12 as an insulin-sensitizing adipokine that is abundantly expressed by fat tissues and designate this a...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 2011

ISSN: 0021-9258

DOI: 10.1074/jbc.m111.277319